Mouse Strain information
APB ID 1228
Added 15/06/2007
Last Edited 10/05/2014
Strain name: C57BL/6JAnu-Dsg4tbird/AnuApb
Nickname: T-Bird
Strain designation name: C57BL/6JAnu-Dsg4tbird/AnuApb
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: desmoglein 4  
Chromosome 18
Affected Gene Symbol Dsg4
Protein expression of altered gene: Unknown
Genetic alteration of gene: ENU-induced mutation
Location on chromosome (bp): 20594676-20630322 bp, + strand (From VEGA annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Synonyms CDHF13, lah
Allele Name T-Bird
Allele Symbol Dsg4tbird
MGI Allele Accession ID MGI:5007752
Ensembl Gene ID: ENSMUSG00000001804
Transcript ID: ENSMUST00000019426
Transcript name: Dsg4-001
bp change: A to C at position 777 on cDNA
Exon number: 6
Exon ID: ENSMUSE00000445469
cDNA position: 777
Amino acid change: Threonine to Proline at position 215
Version: NCBI m37, Ensembl build 62
Mutant Construction Technique None
Phenotype Homozygous State Greasy Coat. Affected mice develop a dull, sparse and greasy coat at about ~40 days of age.
Original Genetic Background C57BL/6
Genetic Background Currently Maintained C57BL/6 x C57BL10
Coat Colour Black
Strain Images
Affected mouse
Affected mouse
Affected mouse
Affected mouse
Strain identification
How is this strain characterised? Phenotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Dermatology
  • Coat
  • greasy
  • hair
  • ENU
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 4 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes



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