Mouse Strain information
Added 06/02/2006
Last Edited 10/05/2014
Strain name: C57BL/6JSfdAnu-Muc2wnn/AnuApb
Nickname: Winnie
Strain designation name: C57BL/6JSfdAnu-Muc2wnn/AnuApb
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: mucin 2  
Chromosome 7
Affected Gene Symbol Muc2
Protein expression of altered gene: Nil
Genetic alteration of gene: ENU induced mutation
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Allele Name Winnie
Allele Symbol Muc2wnn
MGI Allele Accession ID MGI:3614806
Ensembl Gene ID: ENSMUSG00000025515
Transcript ID: ENSMUST00000026590
Transcript name: Muc2-202
bp change: G to A at position 2968 on cDNA
Exon number: 25
Exon ID: ENSMUSE00000467940
cDNA position: 2968
Amino acid change: Cysteine to Tyrosine at position 988
Version: NCBI m37, Ensembl build 57
Mutant Construction Technique None
Phenotype Homozygous State Diarrhoea, soft feces at weaning, some develop rectal prolapse. GIT does not appear inflamed, goblet cell hyperplasia and developmental or functional deficiency - malabsorption syndrome
Original Genetic Background C57BL/6JSfdAnu
Genetic Background Currently Maintained C57BL/6JSfdAnu
Coat Colour Black
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Metabolism
  • diarrhoea
  • malabsorption
  • goblet cell
  • ENU
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 7 mice)

APB stock genotyped verified by: The APF
Are live mice available? No
MTA needs to be signed? Yes



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