Mouse Strain information
APB ID 51
Added 06/02/2006
Last Edited 10/05/2014
Strain name: B6JSfdAnu;NODAnu-Eedlusk/AnuApb
Nickname: LeukSkywalker, ENU3strain:004
Strain designation name: B6SfdAnu;NODAnu-Eedlusk/AnuApb
Genetics
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: embryonic ectoderm development  
Chromosome 7
Affected Gene Symbol Eed
Protein expression of altered gene: Nil
Genetic alteration of gene: ENU induced mutation
Location on chromosome (bp): 97103166-97129493 bp, - strand (From VEGA annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:95286
Synonyms l(7)5Rn, l7Rn5
Allele Name LeukSkywalker
Allele Symbol Eedlusk
MGI Allele Accession ID MGI:3611895
Ensembl Gene ID: ENSMUSG00000030619
Transcript ID: ENSMUST00000107234
Transcript name: Eed-001
bp change: T to C
Intron number: 4
Genomic position: 97120003
Sequence:
97120033gtttttatagccctggtttaagaaatttgaTaagtacatcagaactttgaaaacgaattctcgenomic (reverse strand)
    Exons
Version: NCBI m37, Ensembl build 55
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Dwarf, dilute coat, possible leukemia
Original Genetic Background C57BL/6
Genetic Background Currently Maintained C57BL/6JSfdAnu x NOD
Strain identification
How is this strain characterised? Genotyping
PCR protocols Leuk Skywalker -D7Mit235 (37.2cM)
Leuk Skywalker B -D7Mit213 (28.4cM)
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Developmental biology
Cancer
Keywords
  • leukaemia
  • dwarfism
  • ENU
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 15 mice)

APB stock genotyped verified by: The APF
Are live mice available? No
MTA needs to be signed? Yes


   

 


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