Mouse Strain information
APB ID 4839
Added 24/09/2009
Last Edited 10/05/2014
Strain name: STOCK Muc2keny/AnuApb
Nickname: Kenny ; ENU9CAT:040
Strain designation name: STOCK Muc2keny/AnuApb
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: mucin 2  
Chromosome 7
Affected Gene Symbol Muc2
Protein expression of altered gene: Unknown
Genetic alteration of gene: ENU-induced mutant
Location on chromosome (bp): 148930725-148940442 bp, + strand (From NCBI annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Allele Name kenny
Allele Symbol Muc2keny
MGI Allele Accession ID MGI:4820425
Ensembl Gene ID: ENSMUSG00000025515
Transcript ID: ENSMUST00000026590
Transcript name: Muc2-202
bp change: C to A at position 4192 on cDNA
Exon number: 31
Exon ID: ENSMUSE00000519387
cDNA position: 4192
Amino acid change: Serine to STOP at position 1396
Version: NCBI m37, Ensembl build 55
Mutant Construction Technique None
Phenotype Homozygous State Diarrhoea. Multiple plaques on GIT and lymphomegaly. Other mutants homozygote for a point mutation have soft feces at weaning and develop diarrhea associated with malapsorption syndrome. Homozygous null mutants pass blood in their feces at 6 months, and 65% of null mutants have intestinal tumors at 1 year.
Original Genetic Background C57BL/6 x B10.BR x CBA
Genetic Background Currently Maintained C57BL/6 x CB10.BR x CBA
Coat Colour Black
Eye Colour Black
Strain identification
How is this strain characterised? Phenotyping
Phenotyping technique: Visual appearance
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Immunology and inflammation
Developmental biology
  • malabsorption
  • colon
  • goblet cells
  • diarrhoea
  • ENU
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 5 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes



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