Mouse Strain information
APB ID 4800
Added 10/09/2009
Last Edited 10/05/2014
Strain name: C57BL/6JAnu-Ptprcrain/AnuApb
Nickname: Rain ; ENU11B6:226b
Strain designation name: C57BL/6JAnu-Ptprcrain/AnuApb
Genetics
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: protein tyrosine phosphatase, receptor type, C  
Chromosome 1
Affected Gene Symbol Ptprc
Protein expression of altered gene: Unknown
Genetic alteration of gene: ENU-induced mutation
Location on chromosome (bp): 139959992-140071843 bp, - strand (From Ensembl annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:97810
Synonyms B220, CD45, Ly-5, Lyt-4, T200
Allele Name rain
Allele Symbol Ptprcrain
MGI Allele Accession ID MGI:4819248
Ensembl Gene ID: ENSMUSG00000026395
Transcript ID: ENSMUST00000027645
Transcript name: Ptprc-201
bp change: T to C
Intron number: 11
Genomic position: 140007727
Sequence:
140007757TGTTATAAATGTGCAGACAGATTTGGGGAgTaagtatatcgtttatgtttataaaataaatagenomic (reverse strand)
    Exons
Version: NCBI m37, Ensembl build 55
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Shifted CD45 expression measured by flow cytometry
Original Genetic Background C57BL/6JAnu
Genetic Background Currently Maintained C57BL/6JAnu
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Immunology and inflammation
Keywords
  • cd45
  • signal transduction
  • T cell
  • ENU
  • NIH
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 8 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes


   

 


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