Mouse Strain information
APB ID 4799
Added 10/09/2009
Last Edited 10/05/2014
Strain name: C57BL/6JAnu-Ighddmit/AnuApb
Nickname: Dimit; ENU13NIH:039ab
Strain designation name: C57BL/6JAnu-Ighddmit/AnuApb
Genetics
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: immunoglobulin heavy constant delta  
Chromosome 12
Affected Gene Symbol Ighd
Protein expression of altered gene: Unknown
Genetic alteration of gene: ENU-induced mutation
Location on chromosome (bp): 114647791-114654535 bp, - strand (From Ensembl annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:96447
Synonyms IgD
Allele Name dimit
Allele Symbol Ighddmit
MGI Allele Accession ID MGI:4819235
Ensembl Gene ID: ENSMUSG00000076616
Transcript ID: ENSMUST00000103424
Transcript name: Igh-5-201
bp change: T to A at position 241 on cDNA
Exon number: 1
Exon ID: ENSMUSE00000663372
cDNA position: 241
Amino acid change: Isoleucine to Lysine at position 74
Sequence:
211CAGAACTGAACCTCAACCACACTTGCACCATAAATAAACCCAAAAGGAAAGAAAAACCTTTcDNA (reverse strand)
71-S--E--L--N--L--N--H--T--C--T--I--N--K--P--K--R--K--E--K--P--protein
Version: NCBI m37, Ensembl build 55
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Shifted IgD expression measured by flow cytometry
Original Genetic Background C57BL/6JAnu
Genetic Background Currently Maintained C57BL/JAnu
Coat Colour Black
Eye Colour Black
Strain identification
PCR protocols ENU13NIH39b (amplifluor)
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Immunology and inflammation
Keywords
  • IgD
  • immunoglobulin
  • B cell
  • ENU
  • NIH
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 4 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes


   

 


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