Mouse Strain information
APB ID 4589
Added 11/03/2009
Last Edited 10/05/2014
Strain name: C57BL/6JAnu-Rag1coln/AnuApb
Nickname: Collins ; ENU12NIH:065b
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: recombination activating gene 1  
Chromosome 2
Affected Gene Symbol Rag1
Protein expression of altered gene: Unknown
Genetic alteration of gene: ENU induced mutation.
Location on chromosome (bp): 101478439-101489658 bp, - strand (From VEGA annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Synonyms Rag-1
Allele Name collins
Allele Symbol Rag1coln
MGI Allele Accession ID MGI:4819232
Ensembl Gene ID: ENSMUSG00000061311
Transcript ID: ENSMUST00000078494
Transcript name: Rag1-001
bp change: C to T at position 1079 on cDNA
Exon number: 2
Exon ID: ENSMUSE00000471535
cDNA position: 1079
Amino acid change: Arginine to STOP at position 328
Version: NCBI m37, Ensembl build 56
Mutant Construction Technique None
Phenotype Homozygous State No B or T cells
Original Genetic Background C57BL/6JAnu
Genetic Background Currently Maintained C57BL/6JAnu
Coat Colour Black
Strain Images
Flow cytometry data from control and affected animals. Affecteds are depicted in plots #4, 14, 15
Flow cytometry data from control and affected animals. Affecteds are depicted in plots #4, 14, 15
Strain identification
How is this strain characterised? Genotyping
PCR protocols ENU12NIH65b (amplifluor)
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Immunology and inflammation
  • T cell
  • B cell
  • maturation
  • ENU
  • NIH
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 8 mice)

APB stock genotyped verified by: The depositor
Are live mice available? No
MTA needs to be signed? Yes



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