Mouse Strain information
APB ID 4525
Added 27/02/2009
Last Edited 10/05/2014
Strain name: C57BL/6JAnu-Ebf1serv/2AnuApb
Nickname: ENU11B6:020b ; Servalan
Strain designation name: C57BL/6JAnu-Ebf1serv/2AnuApb
Genetics
Strain Types Mutant strain
Genetic Details Spontaneous
Chemically induced : ENU
Mode of Inheritance Dominant
1.  Affected Gene Name: early B-cell factor 1  
Chromosome 11
Affected Gene Symbol Ebf1
Protein expression of altered gene: Unknown
Genetic alteration of gene: Spontaneous mutation in the facility C57BL/6JAnu colony. Identified in 3 pedigrees. Complete duplication of exon 11.
Location on chromosome (bp): 44430819-44821593 bp, + strand (From VEGA annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:95275
Synonyms O/E-1, Olf-1, Olf1
Allele Name early B-cell factor 1; Servalan
Allele Symbol Ebf1Serv
MGI Allele Accession ID MGI:5007783
Ensembl Gene ID: ENSMUSG00000057098
Transcript ID: ENSMUST00000081265
Transcript name: Ebf1-001
Version: NCBI m37, Ensembl build 62
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Low B cell numbers in peripheral blood.
Phenotype Heterozygous State Low B cell numbers in peripheral blood.
Original Genetic Background C57BL/6JAnu
Genetic Background Currently Maintained C57BL/6JAnu
Coat Colour Black
Strain identification
How is this strain characterised? Genotyping
Phenotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Immunology and inflammation
Keywords
  • B cell
  • ENU
  • NIH
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 3 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes


   

 


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