Mouse Strain information
Added 06/02/2006
Last Edited 11/05/2014
Strain name: C57BL/6JSfdAnu-Tap2jas/AnuApb
Nickname: Jasmine
Strain designation name: C57BL/6JSfdAnu-Tap2jas/AnuApb
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)  
Chromosome 17
Affected Gene Symbol Tap2
Protein expression of altered gene: Normal
Genetic alteration of gene: ENU induced mutation
Location on chromosome (bp): 34203527-34216321 bp, + strand From VEGA annotation of GRCm38
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Synonyms ABC18, Abcb3, Ham-2, HAM2, Ham2, MTP2, PSF-2, PSF2, RING11, Tap-2, Y1
Allele Name jasmine
Allele Symbol Tap2jas
MGI Allele Accession ID MGI:3611893
Ensembl Gene ID: ENSMUSG00000024339
Transcript ID: ENSMUST00000025197
Transcript name: Tap2-001
bp change: A to C at position 1292 on cDNA
Exon number: 5
Exon ID: ENSMUSE00000141074
cDNA position: 1292
Amino acid change: Threonine to Proline at position 292
Version: NCBI m37, Ensembl build 57
Mutant Construction Technique None
Phenotype Homozygous State No CD8⁺ T cells. Normal CD4⁺ and B cells
Original Genetic Background C57BL/6JSfdAnu
Genetic Background Currently Maintained C57BL/6JSfdAnu
Coat Colour Black
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? No
Does it Model a Human Condition? Yes
Description of human condition: Bare Lymphocyte syndrome type 1
Applicable Research Areas Immunology and inflammation
  • Tap2
  • T cell
  • CD8
  • CD4
  • ENU
  • Tap1
  • Bare Lymphocyte syndrome type 1
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 10 mice)

APB stock genotyped verified by: Unverified
Are live mice available? Unknown
MTA needs to be signed? Yes



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