Mouse Strain information
APB ID 2435
Added 13/01/2008
Last Edited 11/07/2018
Strain name: C57BL/6JSfdAnu-Tg(TLK2mHEL)2Ccg/AnuApb
Nickname: Louise2 ; TLK-2
Strain designation name: C57BL/6JSfdAnu-Tg(TLK2mHEL)2Ccg/AnuApb
Strain Types Mutant strain
Genetic Details Transgenic
Mode of Inheritance Dominant
1.   Transgene: transgene insertion 2, Christopher C Goodnow  
Mutant Construction Technique None
Phenotype Homozygous State Express low levels of membrane bound HEL in thyroid. Low serum levels of HEL detected.
Original Genetic Background C57BL/6JStd
Genetic Background Currently Maintained C57BL/6JStdAnu
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Research tools
Immunology and inflammation
  • autoimmunity
  • B cell
  • tolerance
  • Hen egg lysozyme (HEL)
  • T cell
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 10 mice)

APB stock genotyped verified by: The APF
Are live mice available? Unknown
MTA needs to be signed? Yes



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