Mouse Strain information
APB ID 2421
Added 10/01/2008
Last Edited 11/05/2014
Strain name: B10.NOD-H2g7/AnuApb
Nickname: B10.H2g7
Strain designation name: B10.NOD-H2g7/AnuApb
Genetics
Strain Types Congenic
Major histocompatibility congenic
Genetic Details Congenic
Mode of Inheritance Recessive
1.  Affected Gene Name: histocompatibility-2, MHC  
Chromosome 17
Affected Gene Symbol H2
Protein expression of altered gene: Normal
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:95894
Synonyms H-2, MHC-II
Allele Name g7 variant
Allele Symbol H2g7
MGI Allele Accession ID MGI:3579321
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State The H2 complex contains 3 major classes of highly polymorphic gene sets: class I (H2-K, H2-D, Q, H2-T18 genes), class II (H2-I genes), and class III (H2-S genes). These genes are involved in many processes, including graft rejection, immune response, antigen presentation and complement component. The g7 variant is found in NOD strain
Original Genetic Background NOD
Genetic Background Currently Maintained C57BL/10
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? No
Does it Model a Human Condition? No
Research value of this Strain Diabetes Mellitus
Applicable Research Areas Models for human disease
Cell biology
Research tools
Immunology and inflammation
Keywords
  • MHC
  • diabetes
  • autoimmune disease
  • insulitis
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 10 mice)

APB stock genotyped verified by: The depositor
Are live mice available? No
MTA needs to be signed? Yes


   

 


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