Mouse Strain information
APB ID 2378
Added 14/12/2007
Last Edited 13/06/2011
Strain name: B6Apb;CB-Adamts20hip/Apb
Nickname: ENU8F:030 , Hipster
Strain designation name: B6Apb;CB-Adamts20hip/Apb
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20  
Chromosome 15
Affected Gene Symbol Adamts20
Protein expression of altered gene: Normal
Genetic alteration of gene: ENU-induced mutation. This mutation comprises a G to A transition resulting in replacement of glycine by arginine at amino acid position 1221 of the protein.
Location on chromosome (bp): 94100594-94295849 bp, - strand (From VEGA annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Synonyms ADAMTS-20, bt
Allele Name a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20; hipster
Allele Symbol Adamts20hip
MGI Allele Accession ID MGI:3847117
Ensembl Gene ID: ENSMUSG00000022449
Transcript ID: ENSMUST00000035342
Transcript name: Adamts20-001
bp change: G to A at position 3833 on cDNA
Exon number: 26
Exon ID: ENSMUSE00000646542
cDNA position: 3833
Amino acid change: Glycine to Arginine at position 1221
Version: NCBI m37, Ensembl build 57
Mutant Construction Technique None
Phenotype Homozygous State Coat abnormality. Belted, White spotting. Affected mice develop a white stripe transverse across abdomen or a large white spot in the same location.
Original Genetic Background C57BL/6
Genetic Background Currently Maintained C57BL/6 x CBA
Coat Colour Black or Agouti
Strain Images
Affected mouse
Affected mouse
Affected mouse
Affected mouse
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Research value of this Strain Cell migration, development
Applicable Research Areas Dermatology
Models for human disease
Developmental biology
  • Migration
  • pigment
  • melanocyte
  • stripe, white belly patch
  • ENU
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 12 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes



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