Mouse Strain information
APB ID 2367
Added 14/12/2007
Last Edited 10/05/2014
Strain name: B6;CB-Prkdchanky/AnuApb
Nickname: Mr Hankey ; ENU8CAT:005
Strain designation name: B6;CB-Prkdchanky/AnuApb
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: protein kinase, DNA activated, catalytic polypeptide  
Chromosome 16
Affected Gene Symbol Prkdc
Protein expression of altered gene: Unknown
Genetic alteration of gene: ENU-induced mutation
Location on chromosome (bp): 15637959-15842332 bp, + strand (From VEGA annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Synonyms DNA-PK, DNA-PKcs, DNAPDcs, slip, XRCC7
Allele Name hankey
Allele Symbol Prkdchanky
MGI Allele Accession ID MGI:4820716
Allele synonyms: mr hankey
Ensembl Gene ID: ENSMUSG00000022672
Transcript ID: ENSMUST00000023352
Transcript name: Prkdc-201
bp change: T to A at position 1657 on cDNA
Exon number: 16
Exon ID: ENSMUSE00000282431
cDNA position: 1657
Amino acid change: Leucine to STOP at position 545
Version: NCBI m37, Ensembl build 57
Mutant Construction Technique None
Phenotype Homozygous State Diarrhoea. Lymphopenia
Original Genetic Background C57BL/6 x CBA
Genetic Background Currently Maintained C57BL/6JAnu x CBA/CaJ
Strain identification
How is this strain characterised? Phenotyping
PCR protocols Mr Hankey (amplifluor)
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Gastrointestinal
Developmental biology
  • gut
  • diarrhoea
  • intestine
  • ENU
Is the strain available in any form to other researchers No
APB stock stored as: Cryopreserved sperm (from 4 mice)

APB stock genotyped verified by: Unverified
Are live mice available? Unknown
MTA needs to be signed? Yes



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