Mouse Strain information
APB ID 166
Added 15/04/2006
Last Edited 11/05/2014
Strain name: B6;129S4-Cited1tm1Fmar/Apb
Nickname: CitedLacZ
Strain designation name: B6;129S4-Cited1tm1Fmar/Apb
Genetics
Strain Types Mutant strain
Genetic Details Targeted knockin
Targeted reporter
ES Cell-Line Used J1
Mode of Inheritance X-linked
1.  Affected Gene Name: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1  
Chromosome X
Affected Gene Symbol Cited1
Protein expression of altered gene: Nil
Genetic alteration of gene: LacZ/PGKneo cassette was used to replace part of exon 2 and all of exon 3 such that the entire Cited1 coding region was deleted and the lacZ reporter is driven by the natural ATG of Cited1
Location on chromosome (bp): 96848743-96853525, - strand (From Ensembl annotation of NCBI Build 34)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:108023
Synonyms Msg1
Allele Name targeted mutation 1, Finian Martin
Allele Symbol Cited1tm1Fmar
MGI Allele Accession ID MGI:3623213
Mutant Construction Technique None
Chromosome Location (cM) (MGI) 40.1
Phenotype
Phenotype Homozygous State Results in retarded mammary ductal growth at puberty.
Phenotype Heterozygous State Females have no overt phenotype
Original Genetic Background 129/SvJae (Jaenish lab, MIT) x C57BL/6 (Charles River Labs)
Genetic Background Currently Maintained C57BL/6
Coat Colour Black
Eye Colour Black
Strain identification
How is this strain characterised? Genotyping
PCR protocols Cited1 WT / LacZ
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? Yes
Does it Model a Human Condition? Unknown
Applicable Research Areas Models for human disease
Cancer
Developmental biology
Keywords
  • Cited1
  • mammary gland
  • Wnt inhibitor
  • placenta
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 15 mice)

APB stock genotyped verified by: The depositor
Are live mice available? Unknown
MTA needs to be signed? Yes


   

 


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