Mouse Strain information
APB ID 1513
Added 04/07/2007
Last Edited 11/05/2014
Strain name: B6.Cg-Tg(Edn1-NOS3)22Yky/Apb
Nickname: eNOSTg
Strain designation name: B6.Cg-Tg(Edn1-NOS3)22Yky/Apb
Genetics
Strain Types Mutant strain
Genetic Details Transgenic
Mode of Inheritance Dominant
1.   Transgene: transgene insertion 22, Mitsuhiro Yokoyama  
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Hypotension. Elevated cGMP, plasma nitrate and nitrite levels.
Original Genetic Background C57BL/6 x DBA/2J
Genetic Background Currently Maintained C57BL/6JAnu
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Diabetes
Obesity
Cardiovascular
Immunology and inflammation
Keywords
  • eNOS
  • connexin
  • renal arterioles
  • hypotension
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 9 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes


   

 


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