Mouse Strain information
APB ID 1485
Added 02/07/2007
Last Edited 11/05/2014
Strain name: C57BL/6-Tg(TcraTcrb)1100Mjb/AnuApb
Nickname: B6.OT-1
Genetics
Strain Types Mutant strain
Coisogenic
Genetic Details Transgenic
Mode of Inheritance Dominant
1.   Transgene: transgene insertion 1100, Michael J Bevan  
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Transgenic mice on a C57BL/6 background are somewhat immunodeficient, and may be used to study the role of peptides in positive selection and the response of CD8+ T cells to antigen. Carry OVA-specific, H-2Kb-restricted T cell receptor
Coat Colour Black
Eye Colour Black
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? No
Does it Model a Human Condition? No
Applicable Research Areas Haematology
Immunology and inflammation
Keywords
  • T cell
  • receptor
  • ovalbumin
  • CD8
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 10 mice)
Are live mice available? Unknown
MTA needs to be signed? Yes


   

 


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