Mouse Strain information
APB ID 1236
Added 15/06/2007
Last Edited 08/04/2015
Strain name: B6JSfdAnu;CBA(Cg)-Zbtb16pnky/AnuApb
Nickname: Pinky ; ENU8C:027
Strain designation name: B6JSfdAnu;CBA(Cg)-Zbtb16pnky/AnuApb
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: zinc finger and BTB domain containing 16  
Chromosome 9
Affected Gene Symbol Zbtb16
Protein expression of altered gene: Unknown
Genetic alteration of gene: ENU-induced mutation.
Location on chromosome (bp): 48462416-48644050 bp, - strand (From Ensembl annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

Synonyms Green's luxoid, PLZF, Zfp145
Allele Name pinky
Allele Symbol Zbtb16pnky
MGI Allele Accession ID MGI:4462277
Ensembl Gene ID: ENSMUSG00000066687
Transcript ID: ENSMUST00000093852
Transcript name: Zbtb16-201
bp change: T to A at position 457 on cDNA
Exon number: 2
Exon ID: ENSMUSE00000584531
cDNA position: 457
Amino acid change: Tyrosine to STOP at position 70
Version: NCBI m37, Ensembl build 56
Mutant Construction Technique None
Phenotype Homozygous State Limb deformity. Shortening and angular deformity of hindlimbs with extra digits present in some cases. Deformity affects mouse mobility. Previously described homozygous mutants exhibit abnormal anterior-posterior patterning, with skeletal abnormalities of the limb, especially the hindlimb, and homeotic transformations of anterior skeletal elements into posterior structures. Males develop infertility due to loss of germline cells with age.
Original Genetic Background C57BL/6JSfdAnu
Genetic Background Currently Maintained C57Bl6JSfdAnu x CBA/HAnu
Strain Images
Breeding strategy and pedigree for mice submitted for sperm cryopreservation
Breeding strategy and pedigree for mice submitted for sperm cryopreservation
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Developmental biology
  • limb
  • deformity
  • extra digit
  • anterior-posterior patterning
  • ENU
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 12 mice)

APB stock genotyped verified by: The APF
Are live mice available? Unknown
MTA needs to be signed? Yes



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